Target Actionability Review: a systematic evaluation of replication stress as a therapeutic target for paediatric solid malignancies

European Journal of Cancer, 162 (2022): 107-117 (doi:10.1016/j.ejca.2021.11.030)

The 3^rd Target Actionability Review (TAR) is published in the European Journal of Cancer, showing that ATR, CHK1, PARP or WEE1 are the most promising targets using either single agents or in combination with chemotherapy or radiotherapy in neuroblastoma, osteosarcoma, high-grade glioma or medulloblastoma.