Project News
Target Actionability Review: a systematic evaluation of replication stress as a therapeutic target for paediatric solid malignancies
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Project News
European Journal of Cancer, 162 (2022): 107-117 (doi:10.1016/j.ejca.2021.11.030)
The 3rd Target Actionability Review (TAR) is published in the…
The 2nd Target Actionability Review (TAR) on CDK4/6
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Project News
The 2nd Target Actionability Review (TAR) on CDK4/6 as drug targets in pediatric cancers has been finalized by authors of the ITCCP4 consortium.
For…
International Consensus on Minimum Preclinical Testing Requirements for the Development of Innovative Therapies For Children and Adolescents with Cancer
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Project News
Mol Cancer Ther 2021; 20: 1462–8 (doi:10.1158/1535-7163.MCT-20-0394)
This international consensus paper provides recommendations based on the…
Systematic target actionability reviews of preclinical proof-of-concept papers to match targeted drugs to paediatric cancers
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Project News
European Journal of Cancer 2020, 130:168-181 (doi:10.1016/j.ejca.2020.01.027)
The methodology for ITCCP4 Target Actionability Review is published as…
First Target Actionability Review on MDM2 in pediatric cancers published in the European Journal of Cancer
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Project News
European Journal of Cancer 2020, 160:168-181 (doi:10.1016/j.ejca.2020.01.027)
For this extensive, systematic literature review the authors identified…